Detalhe da pesquisa
1.
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice.
Cell
; 183(4): 1070-1085.e12, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33031744
2.
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
Nature
; 586(7830): 560-566, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32854108
3.
Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice.
Hepatology
; 79(1): 183-197, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37540195
4.
Infectious Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Virus in Symptomatic Coronavirus Disease 2019 (COVID-19) Outpatients: Host, Disease, and Viral Correlates.
Clin Infect Dis
; 75(1): e1028-e1036, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35022711
5.
Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
Nature
; 590(7844): E22, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33469219
6.
Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential.
bioRxiv
; 2023 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37425890
7.
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice.
Sci Transl Med
; 14(643): eabm3410, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35315683
8.
Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
bioRxiv
; 2021 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34545367
9.
Infectious SARS-CoV-2 Virus in Symptomatic COVID-19 Outpatients: Host, Disease, and Viral Correlates.
medRxiv
; 2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34100024
10.
A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures.
bioRxiv
; 2020 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511406
11.
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV.
Nat Commun
; 11(1): 222, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31924756
12.
Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.
bioRxiv
; 2020 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511392
13.
Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice.
Cell Rep
; 32(3): 107940, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32668216
14.
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Sci Transl Med
; 12(541)2020 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253226
15.
Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase.
Antiviral Res
; 169: 104541, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31233808